Description
Product Characteristics:
Aliases: Coagulation factor II receptor like 1 antibody, Coagulation factor II receptor-like 1 antibody, Coagulation factor II thrombin receptor like 1 antibody, F2RL1 antibody, G protein coupled receptor 11 antibody, G-protein coupled receptor 11 antibody, GPR11 antibody, PAR 2 antibody, PAR-2 antibody, PAR2_HUMAN antibody, Protease activated receptor 2 antibody, Proteinase activated receptor 2 antibody, Proteinase-activated receptor 2 antibody, Thrombin receptor like 1 antibody, Thrombin receptor-like 1 antibody
Target Information: Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq, Jul 2008]